New asthma pill shows promise in Mid-Stage trial

NCT ID NCT07323654

First seen Jun 26, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study tests an oral drug called KT-621 in 264 adults with moderate to severe eosinophilic asthma that is not well controlled by current treatments. Participants will take either KT-621 or a placebo daily for several weeks. Researchers will measure changes in lung function and asthma control to see if the drug is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KT-621 (oral drug)

What this could lead to

If successful, this could lead to a new daily pill to better control eosinophilic asthma, reducing symptoms and improving lung function.

What could go wrong

This is a mid-stage trial with only 264 people, so results may not apply to everyone. The drug may not work better than placebo or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary eosinophilia T2-high asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kymera Investigative Site

    RECRUITING

    Lancaster, California, 93534, United States

  • Kymera Investigative Site

    RECRUITING

    Long Beach, California, 90815, United States

  • Kymera Investigative Site

    RECRUITING

    Northridge, California, 91324, United States

  • Kymera Investigative Site

    RECRUITING

    Redding, California, 96001, United States

  • Kymera Investigative Site

    RECRUITING

    Upland, California, 91786, United States

  • Kymera Investigative Site

    RECRUITING

    Loxahatchee Groves, Florida, 33470, United States

  • Kymera Investigative Site

    RECRUITING

    Miami, Florida, 33126, United States

  • Kymera Investigative Site

    RECRUITING

    Miami, Florida, 33173, United States

  • Kymera Investigative Site

    RECRUITING

    Miami Lakes, Florida, 33014, United States

  • Kymera Investigative Site

    RECRUITING

    Tampa, Florida, 33607, United States

  • Kymera Investigative Site

    RECRUITING

    East Point, Georgia, 30344, United States

  • Kymera Investigative Site

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • Kymera Investigative Site

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • Kymera Investigative Site

    RECRUITING

    Louisville, Kentucky, 40217, United States

  • Kymera Investigative Site

    RECRUITING

    Chapel Hill, North Carolina, 27517, United States

  • Kymera Investigative Site

    RECRUITING

    Toledo, Ohio, 43617, United States

  • Kymera Investigative Site

    RECRUITING

    Edmond, Oklahoma, 73034, United States

  • Kymera Investigative Site

    RECRUITING

    Clackamas, Oregon, 97015, United States

  • Kymera Investigative Site

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

  • Kymera Investigative Site

    RECRUITING

    Pittsburgh, Pennsylvania, 15241, United States

  • Kymera Investigative Site

    RECRUITING

    North Charleston, South Carolina, 29406, United States

  • Kymera Investigative Site

    RECRUITING

    Rock Hill, South Carolina, 29732, United States

  • Kymera Investigative Site

    RECRUITING

    Chattanooga, Tennessee, 37403, United States

  • Kymera Investigative Site

    RECRUITING

    Dallas, Texas, 75209, United States

  • Kymera Investigative Site

    RECRUITING

    Dallas, Texas, 75246, United States

  • Kymera Investigative Site

    RECRUITING

    McKinney, Texas, 75069, United States

  • Kymera Investigative Site

    RECRUITING

    Madison, Wisconsin, 53792, United States

  • Kymera Investigative Site

    RECRUITING

    Berlin, Germany

  • Kymera Investigative Site

    RECRUITING

    Leipzig, Germany

  • Kymera Investigative Site

    RECRUITING

    Bialystok, Poland

  • Kymera Investigative Site

    RECRUITING

    Gdansk, Poland

  • Kymera Investigative Site

    RECRUITING

    Lodz, Poland

  • Kymera Investigative Site

    RECRUITING

    Poznan, Poland

  • Kymera Investigative Site

    RECRUITING

    Sosnowiec, Poland

  • Kymera Investigative Site

    RECRUITING

    Tarnów, Poland

  • Kymera Investigative Site

    RECRUITING

    Trzebnica, Poland

  • Kymera Investigative Site

    RECRUITING

    Wroclaw, Poland

  • Kymera Investigative Site

    RECRUITING

    Zawadzkie, Poland

  • Kymera Investigative Site

    RECRUITING

    Brasov, Romania

  • Kymera Investigative Site

    RECRUITING

    Craiova, Romania

  • Kymera Investigative Site

    RECRUITING

    Timișoara, Romania

  • Kymera Investigative Site

    RECRUITING

    Belgrade, 11000, Serbia

  • Kymera Investigative Site

    RECRUITING

    Belgrade, Serbia

  • Kymera Investigative Site

    RECRUITING

    Kamenitz, 21204, Serbia

  • Kymera Investigative Site

    RECRUITING

    Užice, 31000, Serbia

  • Kymera Investigative Site

    RECRUITING

    Košice, Slovakia

  • Kymera Investigative Site

    RECRUITING

    Spišská Nová Ves, Slovakia

  • Kymera Investigative Site

    RECRUITING

    Cadiz, Spain

  • Kymera Investigative Site

    RECRUITING

    Jerez de la Frontera, Spain

  • Kymera Investigative Site

    RECRUITING

    Madrid, Spain

  • Kymera Investigative Site

    RECRUITING

    Mataró, Spain

  • Kymera Investigative Site

    RECRUITING

    Santander, Spain

  • Kymera Investigative Site

    RECRUITING

    Bedford, MK40 2FG, United Kingdom

  • Kymera Investigative Site

    RECRUITING

    Birmingham, United Kingdom

  • Kymera Investigative Site

    RECRUITING

    Bristol, United Kingdom

  • Kymera Investigative Site

    RECRUITING

    Leicester, United Kingdom

  • Kymera Investigative Site

    RECRUITING

    London, United Kingdom

  • Kymera Investigative Site

    RECRUITING

    Wythenshawe, United Kingdom