Experimental AATD drug trial halted early: what we know

NCT ID NCT06677307

First seen Dec 29, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This early-stage study tested a new drug, KRRO 110, in healthy volunteers and people with Alpha-1 antitrypsin deficiency (AATD), a genetic condition that can damage the lungs and liver. The main goal was to check safety and how the drug moves through the body. The trial was terminated before completion, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • New Zealand Clinical Research

    Auckland, New Zealand

  • New Zealand Clinical Research

    Christchurch, New Zealand

  • Nucleus Network Pty Ltd

    Melbourne, Victoria, 3004, Australia

  • St. Vincent's Hospital Melbourne

    Melbourne, Victoria, 3065, Australia

  • The Prince Charles Hospital

    Brisbane, Queensland, 4032, Australia

Conditions

Explore the condition pages connected to this study.