New Two-Drug attack on Tough-to-Treat cancers begins human testing

NCT ID NCT06166836

Summary

This study is testing a new combination of two drugs, D-1553 and IN10018, for people with advanced solid tumors that have a specific genetic change called KRAS G12C. The main goals are to find a safe dose for the combination and to see if it can shrink tumors in patients with cancers like colorectal cancer, lung cancer, and others. This is an early-phase trial for adults who have already tried standard treatments.

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Contacts and locations

Locations

  • First Affiliated Hospital of Bengbu Medical College

    Bengbu, China

  • First Affiliated Hospital of Gannan Medical University

    Ganzhou, China

  • Fujian Cancer Hospital

    Fuzhou, China

  • General Hospital Of Eastern Theater Command

    Nanjing, China

  • Henan Cancer Hospital

    Zhengzhou, China

  • Hunan Cancer Hospital

    Changsha, China

  • Renmin Hospital of Wuhan University

    Wuhan, China

  • The first Affiliated Hospital of Zhengzhou University

    Zhengzhou, China

  • Xuzhou Central Hospital

    Xuzhou, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310005, China

Conditions

Explore the condition pages connected to this study.