Which nerve block eases knee surgery pain better?
NCT ID NCT07790393
First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time
Summary
This trial compares two types of nerve blocks, the adductor canal block and the parasartorial compartment block, for pain relief and recovery after arthroscopic knee surgery. Adults scheduled for elective knee surgery will be randomly assigned to receive one of the two blocks. Researchers will measure pain at rest and during movement for 48 hours after surgery, along with opioid use, muscle strength, knee movement, walking ability, side effects, and patient satisfaction. The goal is to find which block provides better pain control while preserving muscle strength and speeding up recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Adductor canal block and parasartorial compartment block, two regional nerve blocks for pain relief
- What this could lead to
- If one block proves better, it could become the preferred choice for knee surgery, offering improved pain control and faster recovery with less opioid use.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to all patients. Nerve blocks carry risks like infection or nerve damage, though rare.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Scheduled for elective unilateral primary arthroscopic knee surgery Exclusion Criteria: * Revision or bilateral arthroscopic knee surgery * Surgery performed for trauma or an emergency indication * Contraindications to regional nerve block, including infection at the injection site, coagulopathy, or inappropriate anticoagulant use * Allergy to amide-type local anesthetics * Pre-existing peripheral neuropathy or motor deficit in the limb to be operated on * Dysfunction of the contralateral limb severe enough to interfere with functional assessments * Chronic opioid use * Severe cognitive impairment * Pregnancy or lactation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medipol Mega Hastaneler Kompleksi
Istanbul, Bagcilar, 34214, Turkey (Türkiye)