New injection shows promise for Worn-Out knees

NCT ID NCT06865079

Summary

This study is testing whether four weekly injections of an experimental drug called TPX-100 can help people with knee arthritis. Researchers will compare TPX-100 to placebo injections in 270 adults aged 50-80 over 53 weeks. The main goals are to check if the treatment is safe and if it reduces pain while improving knee function and structure.

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Contacts and locations

Locations

  • AMR Kansas City

    Kansas City, Kansas, 64114, United States

  • AMR Knoxville

    Knoxville, Tennessee, 37909, United States

  • AMR Lexington

    Lexington, Kentucky, 40509, United States

  • Accurate Clinical Research

    Houston, Texas, 77089, United States

  • Accurate Clinical Research Inc.

    Lake Charles, Louisiana, 70605, United States

  • Accurate Clinical Research, LLC

    Baytown, Texas, 77521, United States

  • Albuquerque Clinical Trials

    Albuquerque, New Mexico, 87102, United States

  • CORE Orthopaedic Medical Center

    Encinitas, California, 92024, United States

  • CenExel

    Salt Lake City, Utah, 84107, United States

  • Center for Clinical Research

    Winston-Salem, North Carolina, 27103, United States

  • Drug Studies of America

    Marietta, Georgia, 30060, United States

  • Elite Clinical Network

    Scottsdale, Arizona, 85260, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78229, United States

  • First Surgical Hospital

    Bellaire, Texas, 77401, United States

  • Hightower Clinical

    Oklahoma City, Oklahoma, 73102, United States

  • K2 Medical Research

    Maitland, Florida, 32751, United States

  • Las Mercedes Medical Research

    Miami, Florida, 33196, United States

  • Las Vegas Clinical Trials

    North Las Vegas, Nevada, 89030, United States

  • Legent Orthopedic Hospital

    Carrolton, California, 75006, United States

  • Marvel Clinical Research (Elite Clinical Network)

    Huntington Beach, California, 92647, United States

  • Mayo Clinic (Rochester)

    Rochester, Minnesota, 55905, United States

  • Medvin Clinical Research

    Covina, California, 91722, United States

  • Medvin Clinical Research Center

    Riverside, California, 92518, United States

  • Medvin Clinical Research Center

    Tujunga, California, 91042, United States

  • Medvin Clinical Research Center

    Whittier, California, 90602, United States

  • Noble Clinical Research

    Tucson, Arizona, 85704, United States

  • Texas Orthopedic Specialist

    Bedford, Texas, 76021, United States

  • University Orthopedics Center

    Altoona, Pennsylvania, 16602, United States

  • University Orthopedics Center

    State College, Pennsylvania, 16801, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • Wasatch Clinical Research

    Salt Lake City, Utah, 84107, United States

  • Well Pharma Medical Research

    Miami, Florida, 33173, United States

  • Wellness Research Center

    Miami, Florida, 33135, United States

Conditions

Explore the condition pages connected to this study.