New hope for HER2 breast cancer: experimental combo faces standard care in major trial

NCT ID NCT07441460

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a new combination of drugs (KN026 plus HB1801 and chemotherapy) works better than the current standard treatment (trastuzumab, pertuzumab, and chemo) for people with HER2-positive breast cancer that has been surgically removed. About 1800 adults with cancer spread to lymph nodes will take part. The goal is to see if the new combo delays cancer return or death.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 201318, China