New pill could tame fibroid symptoms without surgery
NCT ID NCT05445167
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an oral drug called KLH-2109 in 89 premenopausal Japanese women with uterine fibroids who had heavy bleeding and pain. The goal was to see if the drug could reduce bleeding and pain better than a placebo. The trial was completed and may point to a new way to manage fibroid symptoms without surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
KLH-2109 (oral drug)
What this could lead to
If it works, this could offer a new non-surgical option to reduce heavy bleeding and pain from uterine fibroids.
What could go wrong
This is a small, completed Phase 3 trial in Japanese women only, so results may not apply to other groups. The drug may not work better than placebo, and side effects are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Research Site
Multiple Locations, Japan