New pill could tame fibroid symptoms without surgery
NCT ID NCT05445167
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an oral drug called KLH-2109 in 89 premenopausal Japanese women with uterine fibroids who had heavy bleeding and pain. The goal was to see if the drug could reduce bleeding and pain better than a placebo. The trial was completed and may point to a new way to manage fibroid symptoms without surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- KLH-2109 (oral drug)
- What this could lead to
- If it works, this could offer a new non-surgical option to reduce heavy bleeding and pain from uterine fibroids.
- What could go wrong
- This is a small, completed Phase 3 trial in Japanese women only, so results may not apply to other groups. The drug may not work better than placebo, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical Research Site
Multiple Locations, Japan