New drug trial targets debilitating fatigue in mitochondrial disease

NCT ID NCT05650229

Summary

This study is testing whether an investigational drug called KL1333 can reduce fatigue and improve leg strength and endurance in adults with primary mitochondrial disease. About 180 participants will take either KL1333 or a placebo pill twice daily for 48 weeks, with neither the patients nor the doctors knowing who gets which. The main goals are to see if the drug lessens the impact of fatigue on daily life and improves physical function.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Akron Children's Hospital

    RECRUITING

    Akron, Ohio, 44307, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliera Universitaria Gaetano Martino Messina

    NOT_YET_RECRUITING

    Messina, 98125, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliero Universitaria Pisana

    NOT_YET_RECRUITING

    Pisa, 56126, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de NICE - Hôpital Archet 2

    RECRUITING

    Nice, France

    Contact

  • CIBERER- IDIBAPS, Faculty of Medicine, University of Barcelona

    RECRUITING

    Barcelona, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire (CHU) de Bordeaux - Groupe Hospitalier Pellegrin

    RECRUITING

    Bordeaux, France

    Contact

  • Centre Hospitalier Universitaire de Nice, Hopital Pasteur 2

    RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Copenhagen Neuromuscular Center, Rigshospitalet

    RECRUITING

    Copenhagen, Denmark

    Contact Email: •••••@•••••

    Contact

  • Department of Clinical Neurosciences, Addenbrooke's Hospital

    RECRUITING

    Cambridge, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    NOT_YET_RECRUITING

    Milan, 20133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Universita Cattolica del Sacro Cuore

    NOT_YET_RECRUITING

    Roma, 00168, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Groupe Hospitalier Pitie-Salpetriere

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hopital Roger Salengro, CHRU de Lille

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hopital Universitaire de Bruxelles (H.U.B)/ Academisch Ziekenhuis Brussel

    RECRUITING

    Brussels, Belgium

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital General Universitario de Catalunya

    RECRUITING

    Barcelona, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, Spain

    Contact Email: •••••@•••••

    Contact

  • Hospital de la Santa Creu i Sant Pau

    COMPLETED

    Barcelona, Spain

  • IRCCS Institute of Neurological Sciences of Bologna- Universita di Bologna

    NOT_YET_RECRUITING

    Bologna, 40139, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Victoria Infirmary - The Newcastle Upon Tyne Hospitals NHS Foundation Trust

    RECRUITING

    Newcastle, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Email: •••••@•••••

  • Universitair Ziekenhuis Gent

    RECRUITING

    Ghent, Belgium

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitair Ziekenhuis Leuven Gasthuisberg Campus

    RECRUITING

    Leuven, Belgium

    Contact Email: •••••@•••••

    Contact

  • University College London Hospitals Nhs Foundation Trust

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.