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New hope for tough leukemia: first human trial of KK2845 begins

NCT ID NCT06812104

Recruiting now Disease control Sponsor: Kyowa Kirin Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This early-stage study tests a new drug called KK2845 for adults whose acute myeloid leukemia (AML) has returned or not improved after standard treatments. The goal is to find a safe dose and see how well the body tolerates it. About 72 participants will take part in two phases: first to find the highest safe dose, then to gather more information at that dose.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia hematopoietic and lymphoid system neoplasm Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA RELAPSED OR REFRACTORY AML AND OTHER HEMATOLOGIC MALIGNANCIES

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dokkyo Medical University Hospital

    RECRUITING

    Mibu, Tochigi, 321-0207, Japan

  • Fukushima Medical University Hospital

    RECRUITING

    Fukushima, 960-1295, Japan

  • Hokkaido University Hospital

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Japanese Red Cross Musashino Hospital

    RECRUITING

    Musashino, Tokyo, 180-8610, Japan

  • Japanese Red Cross Nagasaki Genbaku Hospital

    RECRUITING

    Nagasaki, 852-8104, Japan

  • Juntendo University Hospital

    RECRUITING

    Tokyo, 113-8431, Japan

  • Kameda General Hospital

    RECRUITING

    Kamogawa, Chiba, 296-8602, Japan

  • Kanazawa University Hospital

    RECRUITING

    Kanazawa, 920-8641, Japan

  • Kansai Medical University Hospital

    RECRUITING

    Hirakata, Osaka, 573-1191, Japan

  • Kindai University Hospital

    RECRUITING

    Osaka, 589-8511, Japan

  • Kurume University Hospital

    RECRUITING

    Kurume, Fukuoka, 830-0011, Japan

  • Kyushu University Hospital

    RECRUITING

    Fukuoka, 812-8582, Japan

  • Nippon Medical School Hospital

    RECRUITING

    Tokyo, 113-8603, Japan

  • Okayama University Hospital

    RECRUITING

    Okayama, 700-8558, Japan

  • Saitama Medical University Hospital

    RECRUITING

    Saitama, 350-0495, Japan

  • Toranomon Hospital

    RECRUITING

    Tokyo, 105-8470, Japan

  • University of Fukui Hospital

    RECRUITING

    Yoshida, Fukui, 910-1193, Japan

More trials for these conditions

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