New 'Living Drug' trial targets Tough-to-Treat blood cancer

NCT ID NCT06079164

Summary

This early-stage study is testing a new CAR-T cell therapy called KITE-197 for adults with aggressive large B-cell lymphoma that has returned or stopped responding to standard treatments. The study first aims to find a safe dose, then tests how well that dose works at putting the cancer into complete remission. Participants will receive a single infusion of their own genetically modified immune cells and be followed closely for safety and effectiveness.

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Contacts and locations

Locations

  • Cross Cancer Institute

    Edmonton, T6G 1Z2, Canada

  • Henry-Joyce Cancer Clinic

    Nashville, Tennessee, 37232, United States

  • Jewish General Hospital

    Montreal, H3T 1E2, Canada

  • QEII Health Sciences Centre

    Halifax, B3H 2Y9, Canada

  • Royal Brisbane and Women's Hospital

    South Brisbane, Queensland, 4101, Australia

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • St. David's South Austin Medical Center

    Austin, Texas, 78704, United States

  • Swedish Cancer Institute

    Seattle, Washington, 98104, United States

  • Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • The Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.