Kidney transplant breakthrough: could this drug free patients from lifelong pills?

NCT ID NCT04803058

First seen Feb 06, 2026 · Last updated May 24, 2026 · Updated 8 times

Summary

This study tests a drug called siplizumab combined with donor bone marrow cells to see if it can train the immune system to accept a new kidney without needing lifelong anti-rejection drugs. The trial involves 18 kidney transplant recipients from living donors. The main goal is to see if patients can safely stop all immunosuppressants while keeping their kidney healthy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Samsung Medical University

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.