Could a drug switch help teen kidney transplant patients keep their grafts longer?

NCT ID NCT04877288

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 33 times

Summary

This study looks at whether switching teen kidney transplant patients (ages 12-17) from standard anti-rejection drugs to a newer medication called belatacept can help preserve kidney function and improve how consistently they take their medicine. About 102 participants will be randomly assigned to either switch to belatacept or stay on their current regimen. The goal is to see if the switch leads to better kidney health over two years.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Locations

Assistance Publique - Hopitaux de Paris (AP-HP) - Hopital Robert Debre - Centre Hospitalo Universita
RECRUITING

Paris, 75019, France

Contact Phone: •••-•••-••••
Bordeaux University Hospital - Pellegrin-Pediatrics
RECRUITING

Bordeaux, 33076, France

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Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu
RECRUITING

Nantes, Loire-Atlantique, 44093, France

Contact Phone: •••-•••-••••
Emma Children (AMC)
RECRUITING

Amsterdam, 1105 AZ, Netherlands

Contact Phone: •••-•••-••••
Hopital De La Timone
RECRUITING

Marseille, 13005, France

Contact Phone: •••-•••-••••
Hopital Necker
RECRUITING

Paris, 75015, France

Contact Phone: •••-•••-••••
Hospices Civils de Lyon - Hôpital Femme Mère Enfant-néphrologie pédiatrique
RECRUITING

Bron, 69677, France

Contact Phone: •••-•••-••••
IRCCS Istituto Giannina Gaslini
RECRUITING

Genoa, Liguria, 16147, Italy

Contact Phone: •••-•••-••••
Local Institution - 0001
COMPLETED

Barcelona, 08035, Spain
Local Institution - 0003
COMPLETED

Seville, 41013, Spain
Local Institution - 0008
COMPLETED

Manchester, M13 9WL, United Kingdom
Local Institution - 0011
RECRUITING

Hamburg, 20246, Germany

Contact
Local Institution - 0012
COMPLETED

Rivas-Vaciamadrid, 28523, Spain
Local Institution - 0014
WITHDRAWN

Washington D.C., District of Columbia, 20010, United States
Local Institution - 0017
WITHDRAWN

Baltimore, Maryland, 21287, United States
Local Institution - 0022
WITHDRAWN

Hollywood, Florida, 33021, United States
Local Institution - 0024
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Durham, North Carolina, 27710, United States
Local Institution - 0025
WITHDRAWN

Cincinnati, Ohio, 45229, United States
Local Institution - 0026
RECRUITING

Heidelberg, 69120, Germany

Contact
Local Institution - 0030
WITHDRAWN

Milan, 20122, Italy
Local Institution - 0033
WITHDRAWN

Chicago, Illinois, 60611, United States
Local Institution - 0038
WITHDRAWN

Seattle, Washington, 98105, United States
Local Institution - 0041
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Los Angeles, California, 90095, United States
Local Institution - 0042
WITHDRAWN

Birmingham, Alabama, 35233, United States
Local Institution - 0043
WITHDRAWN

St Louis, Missouri, 63110, United States
Local Institution - 0044
WITHDRAWN

Boston, Massachusetts, 02115, United States
Local Institution - 0045
WITHDRAWN

Miami, Florida, 33136, United States
Local Institution - 0048
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Cleveland, Ohio, 44124, United States
Local Institution - 0049
WITHDRAWN

Atlanta, Georgia, 30322, United States
Local Institution - 0052
WITHDRAWN

Portland, Oregon, 97239, United States
Local Institution - 0060
NOT_YET_RECRUITING

ABB, Buenos Aires F.D., C1199ABB, Argentina

Contact
Local Institution - 0061
WITHDRAWN

Oslo, N-0027, Norway
Local Institution - 0062
NOT_YET_RECRUITING

Buenos Aires, 1425, Argentina

Contact
Ospedale Regina Margherita-S.C Nefrologia, Dialisi e Trapianto Renale
RECRUITING

Torino, 10126, Italy

Contact Phone: •••-•••-••••
Queen's Medical Centre, Nottingham University Hospitals-Children's Clinical Research Team
RECRUITING

Nottingham, NG7 2UH, United Kingdom

Contact Phone: •••-•••-••••
UZ Gent-Paediatric Nephrology and Rheumatology Department
RECRUITING

Ghent, 9000, Belgium

Contact Phone: •••-•••-••••
Universitaetsklinikum Essen
RECRUITING

Essen, North Rhine-Westphalia, 45122, Germany

Contact Phone: •••-•••-••••
Universitaetsklinikum Koeln-Klinik und Poliklinik für Kinder- und Jugendmedizin, Abteilung für Pädia
RECRUITING

Cologne, 50937, Germany

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

RENAL ALLOGRAFT RECIPIENTS