Ultra-Runners' kidneys under the microscope: new study aims to prevent Race-Day injury

NCT ID NCT07519408

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 30 runners in the Western States Endurance Run, a 100-mile race, to see how their kidneys handle the extreme stress. Researchers will use sensitive urine tests to detect early signs of kidney injury and test whether a sodium bicarbonate supplement can help. The goal is to better understand and reduce kidney risks for endurance athletes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sodium Bicarbonate (dietary supplement) and Placebo

What this could lead to

If successful, this study could help identify risk factors for kidney stress during extreme endurance events and guide safer training and medical practices.

What could go wrong

This is a small, early-stage observational study with only 30 participants, so results may not apply to all runners. The supplement tested may not reduce kidney injury as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.