New drug targets genetic cause of kidney damage

NCT ID NCT06830629

Recruiting now Disease control Sponsor: Maze Therapeutics Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called MZE829 in adults with chronic kidney disease who have a specific high-risk genetic type (APOL1). The main goals are to see if the drug is safe and if it can reduce the amount of protein leaking into the urine, which is a sign of kidney damage. About 56 participants will take the drug and be monitored for 12 weeks.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Decatur, Alabama, 35601, United States
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Huntsville, Alabama, 35805, United States
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Montgomery, Alabama, 36117, United States
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Granada Hills, California, 91344, United States
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Bloomfield, Connecticut, 06112, United States
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Atlantis, Florida, 33462, United States
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Brandon, Florida, 33511, United States
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Brooksville, Florida, 34613, United States
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Hollywood, Florida, 33024, United States
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Melbourne, Florida, 32901, United States
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Miami Lakes, Florida, 33014, United States
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Orlando, Florida, 32822, United States
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College Park, Georgia, 30349, United States
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Cordele, Georgia, 31015, United States
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Macon, Georgia, 31210, United States
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Riverdale, Georgia, 30274, United States
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Savannah, Georgia, 31406, United States
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Chicago, Illinois, 60643, United States
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Kansas City, Kansas, 66112, United States
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Bowling Green, Kentucky, 42101, United States
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Louisville, Kentucky, 40205, United States
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Arnold, Maryland, 21012, United States
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Baltimore, Maryland, 21213, United States
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Lutherville, Maryland, 21093, United States
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Oxon Hill, Maryland, 20745, United States
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Dearborn, Michigan, 48126, United States
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Flint, Michigan, 48503, United States
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Pontiac, Michigan, 48341, United States
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Saint Joseph, Michigan, 49085, United States
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Shelby, Michigan, 48092, United States
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Minneapolis, Minnesota, 55404, United States
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Fayette, Mississippi, 39069, United States
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Ridgeland, Mississippi, 39157, United States
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Tupelo, Mississippi, 38801, United States
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City of Saint Peters, Missouri, 63376, United States
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St Louis, Missouri, 63103, United States
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Las Vegas, Nevada, 89107, United States
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Laurelton, New York, 11413, United States
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Maspeth, New York, 11378, United States
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New York, New York, 10021, United States
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Durham, North Carolina, 27708, United States
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Fayetteville, North Carolina, 28304, United States
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Greensboro, North Carolina, 27405, United States
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Shelby, North Carolina, 28150, United States
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Cincinnati, Ohio, 45267, United States
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Cleveland, Ohio, 44106, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43215, United States
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Ardmore, Oklahoma, 73401, United States
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Upland, Pennsylvania, 19013, United States
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Columbia, South Carolina, 29203, United States
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Spartanburg, South Carolina, 29302, United States
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Spartanburg, South Carolina, 29306, United States
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Chattanooga, Tennessee, 37404, United States
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Dallas, Texas, 75230, United States
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Dallas, Texas, 75246, United States
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Greenville, Texas, 75402, United States
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Houston, Texas, 77030, United States
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Houston, Texas, 77054, United States
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Houston, Texas, 77099, United States
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McKinney, Texas, 75069, United States
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San Antonio, Texas, 78251, United States
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Shenandoah, Texas, 77384, United States
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Sherman, Texas, 75092, United States
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Hampton, Virginia, 23666, United States
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Norfolk, Virginia, 23504, United States
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Créteil, 94010, France
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Lyon, 69347, France
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Paris, 75015, France
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Paris, 75020, France
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Saint-Ouen, 93400, France
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Leicester, LE5 4PW, United Kingdom
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London, SE19RT, United Kingdom
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London, SE59RS, United Kingdom

Conditions

Explore the condition pages connected to this study.

PROTEINURIC KIDNEY DISEASE