New combo therapy battles advanced kidney cancer in major trial

NCT ID NCT04394975

First seen Nov 28, 2025 · Last updated Apr 06, 2026 · Updated 16 times

Summary

This large, completed Phase 3 trial compared a new two-drug combination (toripalimab plus axitinib) against the standard single-drug therapy (sunitinib) for people with advanced kidney cancer that cannot be removed by surgery. The main goal was to see if the combination could keep the cancer from growing for a longer time. The study involved 421 adults who had not received prior drug treatment for their advanced cancer.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, China

Conditions

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