New dosing schedule could improve sickle cell treatment for kids

NCT ID NCT06578507

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 32 times

Summary

This study looks at whether giving hydroxycarbamide twice a day works better than once a day for children with sickle cell disease. About 50 children aged 9 months to 11 years will take the medicine every day for 12 months. Researchers will measure drug levels in the blood and check for safety and effectiveness.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Centre Hospitalier Intercommunal Créteil

    RECRUITING

    Créteil, France

    Contact

    Contact

  • Centre hospitalier de Cayenne

    RECRUITING

    Cayenne, French Guiana

    Contact

    Contact

  • GHEF- Site de Marne-la-Vallée

    RECRUITING

    Jossigny, France

    Contact Email: •••••@•••••

  • Hôpital Bicêtre

    RECRUITING

    Le Kremlin-Bicêtre, France

    Contact

    Contact

  • Hôpital Necker-Enfants malades

    RECRUITING

    Paris, France

    Contact

    Contact

  • Institut d'Hématologie et d'oncologie pédiatrique - IHOPe

    ACTIVE_NOT_RECRUITING

    Lyon, France

Conditions

Explore the condition pages connected to this study.