Tooth decay cure? new drug grows dentin in wisdom teeth
NCT ID NCT06580678
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This early study tested a drug called KH001 to see if it could help teeth naturally repair deep cavities. Twelve adults with a decayed wisdom tooth received the treatment. Researchers then checked the teeth for new dentin growth and monitored for side effects.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
12 people
The number who actually took part.
- Started
-
Nov 2024
- Finished
-
May 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
19 to 35 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Is between 19 and 35 of age by the time of the screening * Has signed written informed consent in the study * Subject who either have no pain in the affected tooth, or can endure pain until the day of tooth extraction Exclusion Criteria: * Is allergic to the active ingredient or other ingredients used in the investigational product * Have participated in another clinical study within 30 days from screening visit and have a history of administration/application of investigational product/device * Is judged by the investigator as ineligible for participation for other reasens
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Seoul National University Dental Hospital
Seoul, 03080, South Korea
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Other studies related to the condition(s) this trial covers.
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