Ketone drink tested for kidney and blood pressure benefits in hypertension
NCT ID NCT06418074
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special ketone drink (KE4) could improve kidney function and lower blood pressure in 20 people with essential hypertension. Participants took the drink or a placebo for five days, then switched after a break. The goal was to see changes in blood pressure, kidney blood flow, and sodium handling. This is a small, early-stage trial meant to gather information, not to prove a treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketone monoester (KE4) drink
- What this could lead to
- If successful, this could point toward a new dietary approach to help manage blood pressure and protect kidney function in people with hypertension.
- What could go wrong
- This is a very small, early-stage trial with only 20 participants. The results may not apply to everyone, and the ketone drink might cause side effects like stomach upset.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The University Clinic in Nephrology and Hypertension, Gødstrup Region Hospital
Herning, 7400, Denmark
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