New drug combo may prevent dangerous blood pressure drops during anesthesia in seniors
NCT ID NCT07002073
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two different drug mixtures—Ketodex and Ketofol—to see which one causes fewer dangerous drops in blood pressure when putting elderly patients (over 65) to sleep for surgery. 102 participants having non-cardiac surgery were randomly assigned to receive one of the two mixtures. The main goal was to measure how often blood pressure fell too low from the start of anesthesia until 16 minutes after breathing tube placement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine-dexmedetomidine (Ketodex) and propofol-ketamine (Ketofol) drug mixtures
What this could lead to
If one mixture causes fewer dangerous drops in blood pressure, it could become a safer way to put elderly patients to sleep for surgery.
What could go wrong
This is a small, completed study with only 102 participants, so results may not apply to all elderly patients or surgeries. The drugs themselves can still cause side effects like low blood pressure or slow heart rate.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cairo University Hospitals
Cairo, Giza Governorate, Egypt