Could a ketamine boost extend pain relief in elderly surgery?
NCT ID NCT07520487
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a low dose of ketamine to standard spinal anesthesia can keep the leg numb longer in patients aged 65 and older having lower limb surgery. Sixty-one participants will be randomly assigned to receive either ketamine or a placebo (saline) alongside their spinal block. The main goal is to measure how long it takes for sensation to return, which could improve pain control and recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketamine
- What this could lead to
- If it works, this could offer a simple way to extend pain relief during and after leg surgery in older adults, potentially reducing the need for additional painkillers.
- What could go wrong
- This is a small, early-phase trial with only 61 participants, so results may not apply broadly. Ketamine can cause side effects like dizziness or confusion, especially in elderly patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cairo university hospitals
RECRUITINGCairo, Giza Governorate, Egypt