Could a ketamine boost extend pain relief in elderly surgery?
NCT ID NCT07520487
First seen Apr 12, 2026 · Last updated Jun 24, 2026 · Updated 14 times
Summary
This study tests whether adding a low dose of ketamine to standard spinal anesthesia can keep the leg numb longer in patients aged 65 and older having lower limb surgery. Sixty-one participants will be randomly assigned to receive either ketamine or a placebo (saline) alongside their spinal block. The main goal is to measure how long it takes for sensation to return, which could improve pain control and recovery.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cairo university hospitals
RECRUITINGCairo, Giza Governorate, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine
What this could lead to
If it works, this could offer a simple way to extend pain relief during and after leg surgery in older adults, potentially reducing the need for additional painkillers.
What could go wrong
This is a small, early-phase trial with only 61 participants, so results may not apply broadly. Ketamine can cause side effects like dizziness or confusion, especially in elderly patients.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.