New hope for kids with devastating epilepsy: experimental drug enters human trials
NCT ID NCT07227857
First seen Nov 14, 2025 · Last updated May 14, 2026 · Updated 26 times
Summary
This study tests an experimental drug (S230815) in 20 children aged 2–12 with a rare, severe epilepsy caused by changes in the KCNT1 gene. The drug is given via spinal injection to see if it is safe and can help control seizures. The trial has two parts: first, finding the right dose, then a longer treatment period to monitor effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedaliera Universitaria Meyer IRCCS
NOT_YET_RECRUITINGFlorence, 50139, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Boston Children's Hospital
NOT_YET_RECRUITINGBoston, Massachusetts, 02115, United States
Contact Email: •••••@•••••
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Children's Health Dallas
NOT_YET_RECRUITINGDallas, Texas, 75235, United States
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Children's Hospital of Orange County
NOT_YET_RECRUITINGOrange, California, 92868, United States
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Hopital Necker Enfants Malades
RECRUITINGParis, 75015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Ruber Internacional
RECRUITINGMadrid, 28035, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Sant Joan De Deu Barcelona
RECRUITINGEsplugues de Llobregat, 08950, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Des Neurosciences De La Timone
RECRUITINGMarseille, 13005, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nationwide Children's Hospital
NOT_YET_RECRUITINGColumbus, Ohio, 43205, United States
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Osaka City General Hospital
RECRUITINGOsaka, Japan
Contact
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Ospedale Pediatrico Bambino Gesu
NOT_YET_RECRUITINGRoma, 00165, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Robert Debre University Hospital
RECRUITINGParis, 75019, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shinshu University Hospital
RECRUITINGNagano, Japan
Contact
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Shizuoka Institute of Epilepsy and Neurological Disorders
RECRUITINGShizuoka, Japan
Contact
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The Children's Hospital of Philadelphia
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Rochester Medical Center
NOT_YET_RECRUITINGRochester, New York, 14642, United States
Conditions
Explore the condition pages connected to this study.