First human test of new Cancer-Fighting antibody begins

NCT ID NCT05501821

Summary

This early-stage study tested the safety and initial effectiveness of a new experimental drug called KBA1412 in adults with advanced solid tumors that have stopped responding to standard treatments. The trial tested KBA1412 given alone and in combination with an existing immunotherapy drug (pembrolizumab) to see how well patients tolerated it and if it showed any signs of fighting their cancer. It involved a small group of 16 participants to find the right dose and gather initial safety data.

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Contacts and locations

Locations

  • Dutch Cancer Institute AVL

    Amsterdam, 1066 CX, Netherlands

  • Erasmus Medical Center Rotterdam

    Rotterdam, 3015 GD, Netherlands

  • University Hospital Antwerp

    Antwerp, 2650, Belgium

  • University Hospital Ghent

    Ghent, 9000, Belgium

  • University Hospital Leiden (LUMC)

    Leiden, 2333 ZA, Netherlands

Conditions

Explore the condition pages connected to this study.