New pill could tame mania in bipolar disorder
NCT ID NCT06951698
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times
Summary
This study tests a new drug called KarXT for people with Bipolar I disorder who are currently having a manic episode (feeling extremely high energy, irritable, or agitated). About 274 adults who need hospital care for mania will receive either KarXT or a placebo for several weeks. The main goal is to see if KarXT reduces manic symptoms better than a placebo, using a standard rating scale.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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"University Multiprofile Hospital for Active Treatment - Dr. Georgi Stranski" EAD
RECRUITINGPleven, 5800, Bulgaria
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Advanced Research Center Inc.
RECRUITINGAnaheim, California, 92805, United States
Contact Phone: •••-•••-••••
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Advanced Research Institute of Miami
RECRUITINGHomestead, Florida, 33033, United States
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CITrials
RECRUITINGBellflower, California, 90706, United States
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Catalina Research Institute, LLC
RECRUITINGMontclair, California, 91763, United States
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CenExel iResearch, LLC
RECRUITINGSavannah, Georgia, 31405, United States
Contact Phone: •••-•••-••••
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Center for Mental Health Prof. Dr. Ivan Temkov
RECRUITINGBurgas, 8001, Bulgaria
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Centrum Medyczne HCP
RECRUITINGPoznan, Greater Poland Voivodeship, 61-485, Poland
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Clinica Inventiva
RECRUITINGTuszyn, 95-080, Poland
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Collaborative Neuroscience Research, LLC
RECRUITINGLong Beach, California, 90806, United States
Contact Phone: •••-•••-••••
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Connecticut Mental Health Center
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact Phone: •••-•••-••••
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Goryokai Medical Corporation - Goryokai Hospital
RECRUITINGSapporo, Hokkaido, 002-8029, Japan
Contact Phone: •••-•••-••••
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Health Synergy Clinical Research
RECRUITINGWest Palm Beach, Florida, 33407, United States
Contact Phone: •••-•••-••••
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Hospital Italiano de Buenos Aires
RECRUITINGABB, Buenos Aires F.D., C1199ABB, Argentina
Contact Phone: •••-•••-••••
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Hotei Hospital
RECRUITINGKōnan, Aichi-ken, 4838248, Japan
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Innovative Clinical Research, Inc.
RECRUITINGMiami Lakes, Florida, 33016, United States
Contact Phone: •••-•••-••••
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Instytut Psychiatrii i Neurologii
RECRUITINGWarsaw, Masovian Voivodeship, 02-957, Poland
Contact Phone: •••-•••-••••
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Kansai Medical University Medical Center
RECRUITINGMoriguchi, Osaka, 570-8507, Japan
Contact Phone: •••-•••-••••
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Klinika Psychiatrii Uniwersytet Medyczny w Białymstoku
RECRUITINGBialystok, Podlaskie Voivodeship, 15-272, Poland
Contact Phone: •••-•••-••••
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Kuramitsu Hospital
RECRUITINGFukuoka, 819-0037, Japan
Contact Phone: •••-•••-••••
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Local Institution - 0014
NOT_YET_RECRUITINGCerritos, California, 90703, United States
Contact
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Local Institution - 0015
NOT_YET_RECRUITINGMiami Lakes, Florida, 33016, United States
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Local Institution - 0029
WITHDRAWNIrving, Texas, 75062, United States
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Local Institution - 0081
WITHDRAWNIruma, Saitama, 350-0495, Japan
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Local Institution - 0084
NOT_YET_RECRUITINGOsaka, 590-0018, Japan
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Local Institution - 0100
WITHDRAWNKitakyushu, Fukuoka, 803-0831, Japan
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Local Institution - 0102
NOT_YET_RECRUITINGSosnowiec, Silesian Voivodeship, 41-200, Poland
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Local Institution - 0108
NOT_YET_RECRUITINGMendoza, 5502, Argentina
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Local Institution - 0109
NOT_YET_RECRUITINGMendoza, 5502, Argentina
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Local Institution - 0111
NOT_YET_RECRUITINGGdansk, Pomeranian Voivodeship, 80-214, Poland
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Local Institution - 0114
NOT_YET_RECRUITINGBudapest, 0, Hungary
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M2M Med
RECRUITINGRybnik, Silesian Voivodeship, 44-200, Poland
Contact Phone: •••-•••-••••
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MHAT "Dr. Ival Seliminski"
RECRUITINGSliven, 8800, Bulgaria
Contact Phone: •••-•••-••••
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Mental Health Center - Vratsa
RECRUITINGVratsa, 3000, Bulgaria
Contact Phone: •••-•••-••••
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Miyazaki Prefectural Miyazaki Hospital
RECRUITINGMiyazaki, 880-8510, Japan
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NRC Research Institute
RECRUITINGOrange, California, 92868, United States
Contact Phone: •••-•••-••••
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Narimasu Kosei Hospital
RECRUITINGtabashi City, Tokyo, 175-0091, Japan
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National Center of Neurology and Psychiatry
RECRUITINGKodaira, Tokyo, 187-8551, Japan
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National Kohnodai Medical Center.
RECRUITINGIchikawa, Chiba, 272-8516, Japan
Contact Phone: •••-•••-••••
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Neuro-Behavioral Clinical Research
RECRUITINGNorth Canton, Ohio, 44720, United States
Contact Phone: •••-•••-••••
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North Shore Hospital
RECRUITINGAuckland, 0622, New Zealand
Contact Phone: •••-•••-••••
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Obihiro Kosei Hospital
RECRUITINGObihiro, Hokkaido, 080-0024, Japan
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Okehazama Hospital
RECRUITINGToyoake, Aichi-ken, 470-1168, Japan
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Osaka Metropolitan University Hospital
RECRUITINGOsaka, 545-8586, Japan
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Petz Aladar Egyetemi Oktato Korhaz
RECRUITINGGyőr, Győr-Moson-Sopron, 9024, Hungary
Contact
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Pillar Clinical Research - Bentonville
RECRUITINGBentonville, Arkansas, 72712, United States
Contact Phone: •••-•••-••••
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Pillar Clinical Research - Richardson
RECRUITINGRichardson, Texas, 75080, United States
Contact Phone: •••-•••-••••
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Pillar Clinical Research -Chicago
RECRUITINGChicago, Illinois, 60641, United States
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Rainbow and Sea Hospital
RECRUITINGKaratsu-shi, Saga-ken, 847-0031, Japan
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Ramsay Clinic New Farm
RECRUITINGBrisbane, Queensland, 4005, Australia
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Ramsay Clinic Northside
RECRUITINGSt Leonards, New South Wales, 2065, Australia
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Research Centers of America ( Hollywood )
RECRUITINGHollywood, Florida, 33024, United States
Contact Phone: •••-•••-••••
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Richmond Behavioral Associates
RECRUITINGStaten Island, New York, 10314, United States
Contact Phone: •••-•••-••••
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Saitama Konan Hospital
RECRUITINGKumagaya, Saitama, 360-0114, Japan
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Sanatorio Morra S.A.
RECRUITINGCórdoba, 5000, Argentina
Contact Phone: •••-•••-••••
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Semmelweis Egyetem
RECRUITINGBudapest, 1083, Hungary
Contact Phone: •••-•••-••••
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Showa Medical University Karasuyama Hospital
RECRUITINGTokyo, 157-8577, Japan
Contact Phone: •••-•••-••••
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South Florida Research Phase I-IV
RECRUITINGMiami, Florida, 33166, United States
Contact Phone: •••-•••-••••
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State Psychiatric Hospital Sv. Ivan Rilski Novi Iskar
RECRUITINGNovi Iskar, 1282, Bulgaria
Contact Phone: •••-•••-••••
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Synexus Clinical Research US, Inc.
RECRUITINGAtlanta, Georgia, 30328, United States
Contact Phone: •••-•••-••••
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Wakayama Medical University Hospital
RECRUITINGWakayama, 641-8510, Japan
Contact Phone: •••-•••-••••
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Woodland International Research Group
RECRUITINGLittle Rock, Arkansas, 72211, United States
Contact Phone: •••-•••-••••
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Yamagata Sakuracho Hospital
RECRUITINGYamagata, 990-0045, Japan
Contact Phone: •••-•••-••••
Conditions
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