Experimental K9 pill tested for thyroid eye disease – but study stopped early

NCT ID NCT06467435

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tested an oral drug called K9 (kamuvudine-9) in people with thyroid eye disease, a condition that causes eye bulging and discomfort. The study planned to enroll up to 10 patients but was terminated after only 4 participants. The main goal was to check safety, not to prove the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Kamuvudine-9 (K9) tablets

What this could lead to

If it works, this could point toward a new oral treatment to control thyroid eye disease symptoms.

What could go wrong

This was a very small, early-phase safety study that was terminated early, so we have little data on effectiveness. The results may not apply to a larger population.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endocrine exophthalmos Graves Ophthalmopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kentucky

    Lexington, Kentucky, 40506, United States