New hope for lung cancer patients: experimental drug JYP0322 takes on chemo

NCT ID NCT07154368

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study tests a new drug called JYP0322 against standard chemotherapy for people with a specific type of advanced lung cancer (ROS1-positive non-small cell lung cancer) that has stopped responding to earlier targeted treatments. About 207 participants will be randomly assigned to receive either JYP0322 or chemotherapy. The main goal is to see if JYP0322 can delay cancer growth longer than chemotherapy. Patients who get chemotherapy may switch to JYP0322 if their cancer gets worse.

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Conditions

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