New shot takes on botox for Post-Stroke arm tightness

NCT ID NCT07292025

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a new drug called JTM201 against Botox in 30 adults who had a stroke at least 6 months ago and still have muscle stiffness in their arm. The goal was to see if JTM201 is safe and can reduce spasticity, making daily tasks like dressing and hygiene easier. The study is already completed, and results will show how it compares to the standard treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JTM201 (a botulinum toxin type A injection, similar to Botox)

What this could lead to

If it works, JTM201 could offer a new option to ease muscle stiffness in the arm after a stroke, improving daily function.

What could go wrong

This is a very early Phase 1 trial with only 30 people, so results may not apply widely. It compares JTM201 to Botox, so it may not prove better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul Boramae Hospital

    Seoul, South Korea