New antibody combo JST-018 enters first human safety trial

NCT ID NCT07595458

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 1 study is testing whether a single injection of JST-018, a mix of three monoclonal antibodies, is safe and tolerable in 48 healthy adults aged 18 to 55. Participants will be monitored for side effects, drug levels in the blood, and immune responses over one year. This is an early step to see if the drug can be studied further for antiviral use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JST-018 (a combination of 3 monoclonal antibodies)

What this could lead to

If safe and well-tolerated, this could pave the way for further studies to see if JST-018 can help fight viral infections.

What could go wrong

This is a very early Phase 1 trial in only 48 healthy people, so it cannot yet tell us if the drug works against any disease. Side effects are possible and will be closely monitored.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • PPD Las Vegas Clinical Research Unit

    RECRUITING

    Las Vegas, Nevada, 89113, United States

    Contact Phone: •••-•••-••••