New hope for HER2+ breast cancer: experimental drug JSKN003 faces off against standard therapy

NCT ID NCT07545044

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 study tests whether a new drug called JSKN003 works better than the current standard therapy for people with HER2-positive breast cancer that has returned or spread. About 60 adults who have not had prior treatment for advanced disease will receive either JSKN003 or a combination of trastuzumab, pertuzumab, and docetaxel. The main goal is to see how many patients' tumors shrink significantly.

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Conditions

The condition(s) this trial relates to.

breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.