New pill aims to quiet heartburn without damaging the esophagus
NCT ID NCT07160790
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new drug called JP-1366 for people with non-erosive gastroesophageal reflux disease (NERD), a condition causing heartburn without visible damage to the esophagus. About 321 adults will take either JP-1366 or a placebo daily. The main goal is to see if the drug increases the number of days without heartburn.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- JP-1366 (a drug for acid reflux)
- What this could lead to
- If it works, this could provide a new treatment option to reduce heartburn in people with non-erosive reflux disease.
- What could go wrong
- This is a Phase 3 trial, but results may not confirm benefit. Side effects are possible, and the drug may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.