New pill shows promise for rare blood cancers in early trial
NCT ID NCT07612280
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a new daily pill called JBI-802 in people with certain blood cancers (myeloproliferative neoplasms and MDS/MPN) who have too many platelets. The trial has two phases: first, finding a safe dose in about 30 adults, then checking if it works. Participants take the drug for up to 2 years if it helps and side effects are manageable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- JBI-802 (a drug that targets two proteins, LSD1 and HDAC6, to help control abnormal blood cell growth)
- What this could lead to
- If this trial succeeds, it could point toward a new oral treatment option for people with certain blood cancers who have too many platelets.
- What could go wrong
- This is an early-phase trial with only 30 participants, so results may not apply to everyone. The drug may cause side effects or not work as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hollywood Private Hospital
RECRUITINGNedlands, 6009, Australia
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Macquarie University
RECRUITINGSydney, New South Wales, 2109, Australia
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Monash Medical Centre
RECRUITINGMelbourne, Victoria, 3168, Australia
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Royal Adelaide Hospital
RECRUITINGAdelaide, South Australia, 5000, Australia
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St Vincent's Hospital (Melbourne)
RECRUITINGMelbourne, Victoria, 3065, Australia
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St. Vincent's Hospital Sydney Limited
RECRUITINGSydney, New South Wales, 2010, Australia
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The Perth Blood Institute Limited
RECRUITINGPerth, Western Australia, 6000, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a pill keep blood cancer at bay after a stem cell transplant?
- Can a hormone mimic curb the need for bloodletting in a blood cancer?
- Can a targeted drug outperform standard care for rare blood cancers?
- Can a Dual-Action pill tame bone marrow tumors?
- Can a Two-Drug combo tame a rare blood cancer?
- Can a new tracer light up cancer growth?