Hair loss protein target revealed? minoxidil study probes JAK2
NCT ID NCT07563036
First seen May 02, 2026 · Last updated Jun 23, 2026 · Updated 5 times
Summary
This study will measure a protein called JAK2 in the scalps of 25 people with male pattern baldness. Researchers will compare JAK2 levels in balding and non-balding areas, then see if 12 weeks of topical minoxidil 5% changes JAK2 in the balding scalp. The goal is to understand whether JAK2 is involved in hair loss and how minoxidil might work at the tissue level.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Kasr El Aini Hospital
RECRUITINGCairo, Cairo Governorate, 11555, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Topical minoxidil 5% solution
What this could lead to
If successful, this could reveal whether JAK2 plays a role in hair loss and whether minoxidil works through this pathway, pointing toward new treatment targets.
What could go wrong
This is a very small, early study with only 25 participants and no control group. It measures a protein level, not hair regrowth directly, so results may not lead to a practical treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.