New drug targets tough cancer mutation in early trial

NCT ID NCT05002270

First seen Jan 15, 2026 · Last updated May 01, 2026 · Updated 13 times

Summary

This study tested a drug called JAB-21822 in 29 adults with advanced solid tumors (like lung or colon cancer) that have a specific genetic change called KRAS G12C. The goal was to see if the drug is safe and can shrink tumors. Participants took the drug alone or with another medication, and researchers monitored side effects and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinc

    Phoenix, Arizona, 85054, United States

  • Mayo Clinc

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinc

    Jacksonville, Florida, 32224, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.