Terminated early: drug combo test for tough cancer halted

NCT ID NCT05921760

Summary

This early-stage study aimed to test the safety and initial effectiveness of a three-drug combination for people with advanced bile duct cancer that has a specific genetic change (IDH1 mutation). The treatment combined a targeted drug (ivosidenib) with two immunotherapy drugs. The trial was stopped early by the sponsor after enrolling only 7 people, so no results on effectiveness are available.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins

    Baltimore, Maryland, 21231, United States

  • UCLH

    London, NW1 2PG, United Kingdom

  • UCSF - Medical Center at Mission Bay

    San Francisco, California, 94158, United States

  • Ucsf Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94158, United States

Conditions

Explore the condition pages connected to this study.