Could immune therapy calm sudden OCD and food refusal in kids?

NCT ID NCT04609761

First seen Mar 08, 2026 · Last updated May 23, 2026 · Updated 8 times

Summary

This study tested a monthly infusion of donated antibodies (IVIG) for 6 months in 17 children aged 4-17 with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), a condition causing sudden severe OCD, anxiety, or food refusal. The goal was to see if the treatment is safe and can reduce symptoms. Since PANS may involve immune system problems, IVIG was chosen to try to calm that response. The study was small and open-label, meaning everyone knew they were getting the drug, so results are preliminary.

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Contacts and locations

Locations

  • Gillberg Neuropsychiatry Centre

    Gothenburg, 411 19, Sweden

Conditions

Explore the condition pages connected to this study.