New drug may shield transplant patients from deadly immune attack

NCT ID NCT07381114

First seen Feb 02, 2026 · Last updated May 15, 2026 · Updated 9 times

Summary

This study tests whether the drug ivarmacitinib can prevent acute graft-versus-host disease (aGVHD) in 32 people with blood cancers receiving a stem cell transplant from a half-matched donor. aGVHD occurs when donor immune cells attack the patient's body. The study will measure how many patients develop aGVHD, infections, and other complications over one year. The goal is to improve recovery and survival after transplant.

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