New combo therapy may beat stubborn fungal infections

This study tested whether adding isotretinoin (a retinoid that changes skin oil and growth) to the standard antifungal itraconazole works better than itraconazole alone for adults with resistant Trichophyton fungal skin infections. 148 adults aged 18-65 with confirmed infection were randomly assigned to one of two groups. The goal was to see if the combination leads to higher cure rates and fewer relapses.