New pill aims to soothe Alzheimer's agitation in major trial

NCT ID NCT06651567

Recruiting now Symptom relief Sponsor: Intra-Cellular Therapies, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 5 times

Summary

This study tests an experimental drug called ITI-1284 to see if it can safely reduce agitation in people with Alzheimer's dementia. About 320 participants will receive either the drug or a placebo, and researchers will measure changes in agitated behaviors using a caregiver questionnaire. The goal is to improve quality of life for patients and their families.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AGITATION ASSOCIATED WITH ALZHEIMER'S DEMENTIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGITATION ASSOCIATED WITH ALZHEIMER'S DEMENTIA

Contacts and locations

Locations

A Shine S R O
RECRUITING

Pilsen, 301 00, Czechia
ATP Clinical Research
RECRUITING

Costa Mesa, California, 92626, United States
Advance Medical Research Center
SUSPENDED

Miami, Florida, 33135, United States
Advanced Clinical Research Network
RECRUITING

Miami, Florida, 33135, United States
Advanced Research Center, Inc
RECRUITING

Anaheim, California, 92805, United States
Allied Biomedical Research Institute (ABRI), Inc
RECRUITING

Miami, Florida, 33155-4630, United States
Bio Behavioral Health
RECRUITING

Toms River, New Jersey, 08755, United States
Brain Matters Research
COMPLETED

Delray Beach, Florida, 33445, United States
Centrul de Evaluarea si Tratament al Toxicodependentelor pentru Tineri Sf. Stelian
RECRUITING

Bucharest, 60222, Romania
Charter Research
RECRUITING

Orlando, Florida, 32803, United States
Clinical Center Dr Dragisa Misovic Dedinje
RECRUITING

Belgrade, 11000, Serbia
Clinical Research of Brandon
RECRUITING

Brandon, Florida, 33511, United States
Clintrial s r o
RECRUITING

Prague, 100 00, Czechia
Combined Research Orlando
COMPLETED

Orlando, Florida, 32807, United States
Crystal Comfort s.r.o.
RECRUITING

Vranov nad Topľou, 09301, Slovakia
DCC 'Sv. Vrach and Sv. Sv. Kuzma and Damyan', OOD
RECRUITING

Sofia, 1408, Bulgaria
Direct Helpers Medical Center, Inc.
RECRUITING

Hialeah, Florida, 33012-3618, United States
Envision Trials LLC
RECRUITING

Bonita Springs, Florida, 34134, United States
Epamed sro
RECRUITING

Košice, 4001, Slovakia
Eximia Clinical Research NC
COMPLETED

Raleigh, North Carolina, 27607, United States
Fakultni nemocnice u sv. Anny v Brne
RECRUITING

Brno, 602 00, Czechia
Homestead Associates in Research Inc
RECRUITING

Homestead, Florida, 33033, United States
Hosp. Gral. de Albacete
RECRUITING

Albacete, 02006, Spain
Hosp. Prov. de Zamora
RECRUITING

Zamora, 49021, Spain
Hosp. Quirónsalud Málaga
RECRUITING

Málaga, 29004, Spain
Hosp. Viamed Montecanal
RECRUITING

Zaragoza, 50012, Spain
Hospital Universitari Germans Trias i Pujol
RECRUITING

Badalona, 08916, Spain
Institute of Mental Health Serbia
RECRUITING

Belgrade, 11000, Serbia
K2 Medical Research
RECRUITING

Maitland, Florida, 32751, United States
Medical Center Hera EOOD
RECRUITING

Sofia, 1510, Bulgaria
Medical Center Intermedica, OOD
RECRUITING

Sofia, 1680, Bulgaria
Medical Center Medconsult-Pleven
RECRUITING

Pleven, 5800, Bulgaria
Mental Health Centre Prof. N Shipkovenski EOOD
RECRUITING

Sofia, 1377, Bulgaria
Miami Jewish Health System
RECRUITING

Miami, Florida, 33180, United States
NEURES s r o
RECRUITING

Krompachy, 05342, Slovakia
NEUROHK s r o
RECRUITING

Choceň, 56501, Czechia
National Institute Of Clinical Research
COMPLETED

Garden Grove, California, 92844, United States
Neurologicka ambulancia MUDr.Dupejova s.r.o.
RECRUITING

Banská Bystrica, 97404, Slovakia
Neurology Associates PA
RECRUITING

Maitland, Florida, 32751, United States
NeuropsychiatrieHK, s.r.o.
RECRUITING

Prague, 160 00, Czechia
Neuroterapie KH S R O
RECRUITING

Kutná Hora, 284 01, Czechia
Oasis Clinical Research LLC
RECRUITING

Las Vegas, Nevada, 89121, United States
Premiere Research Institute at Palm Beach Neurology
RECRUITING

West Palm Beach, Florida, 33407, United States
Psych Me Medical Research Inc
RECRUITING

Tampa, Florida, 33614, United States
Psychiatric Clinic "VRAPCE"
RECRUITING

Zagreb, 10090, Croatia
Psychiatric Hospital Sveti Ivan
RECRUITING

Zagreb, 10090, Croatia
Psychiatricka Ambulancia Centrum Zdravia R.B.K. S.R.O.
RECRUITING

Svidník, 089 01, Slovakia
Quantum Research Associates Corp
RECRUITING

Tampa, Florida, 33614, United States
SC Carpe Diem SRL
RECRUITING

Sibiu, 550281, Romania
SFM Clinical Research LLC
RECRUITING

Boca Raton, Florida, 33487, United States
Science Connections LLC
RECRUITING

Doral, Florida, 33178, United States
South Florida Research Phase I-IV
RECRUITING

Miami, Florida, 33166, United States
Special Hospital for Psychiatric Diseases Kovin
COMPLETED

Kovin, 26220, Serbia
Special Hospital for Psychiatric Diseases Sveti Vracevi
RECRUITING

Novi Kneževac, 23330, Serbia
Spitalul Clinic de Psihiatrie Prof Dr Alexandru Obregia
RECRUITING

Bucharest, 041914, Romania
Spitalul Clinic de Psihiatrie Prof Dr Alexandru Obregia 1
RECRUITING

Bucharest, 040874, Romania
Spitalul Universitar de Urgenta Militar Central 'Dr. Carol Davila'
RECRUITING

Bucharest, 010825, Romania
Spitalul de Psihiatrie si Neurologie Brasov
RECRUITING

Com Sanpetru, 507190, Romania
State Psychiatric Hospital - Lovech
RECRUITING

Lovech, 5500, Bulgaria
Sunshine Medical Research Studies Inc
RECRUITING

Miami, Florida, 33186, United States
Tufts University School of Medicine
RECRUITING

Boston, Massachusetts, 02111, United States
UMHAT Prof. Dr. St. Kirkovich AD
RECRUITING

Stara Zagora, 6003, Bulgaria
UT Health San Antonio
SUSPENDED

San Antonio, Texas, 78229, United States
University Clinical Center NIS
RECRUITING

Niš, 18000, Serbia
University Hospital Centre Zagreb
RECRUITING

Zagreb, 10000, Croatia
University Hospital Centre Zagreb 1
COMPLETED

Zagreb, 10000, Croatia
Univerzitna nemocnica Bratislava
RECRUITING

Bratislava, 81369, Slovakia
Vital Care Research
RECRUITING

Miami, Florida, 33122, United States
Wellness Research Center
RECRUITING

Miami, Florida, 33135, United States
Wr Pri Llc
COMPLETED

Newport Beach, California, 92660, United States