New drug offers hope for sinus sufferers

NCT ID NCT06691113

Ongoing Symptom relief Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 22 times

Summary

This study tests an experimental drug called itepekimab in 60 adults with chronic sinusitis that doesn't improve with standard sprays. The goal is to see if it reduces sinus swelling and symptoms like stuffiness, runny nose, and facial pain. Participants receive either the drug or a placebo for 24 weeks, with follow-up for 20 more weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advanced Research Associates (ARA) Professionals- Site Number : 8400002

Miami, Florida, 33176, United States
Alamo ENT Associates- Site Number : 8400026

San Antonio, Texas, 78258, United States
Allervie Clinical Research - Birmingham- Site Number : 8400006

Birmingham, Alabama, 35209, United States
Azienda Ospedaliero-Universitaria Pisana-Site Number : 3800003

Pisa, 56124, Italy
ENT Associates of Texas - McKinne- Site Number : 8400013

McKinney, Texas, 75070, United States
Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400007

Norfolk, Virginia, 23510, United States
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Site Number : 3800001

Rome, Roma, 00168, Italy
Fondazione Policlinico Universitario Campus Bio-Medico-Site Number : 3800002

Rome, Roma, 00128, Italy
Investigational Site Number : 0320001

Buenos Aires, 1425, Argentina
Investigational Site Number : 0320003

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Investigational Site Number : 0320004

Corrientes, 3400, Argentina
Investigational Site Number : 0560001

Leuven, 3000, Belgium
Investigational Site Number : 0560002

Ghent, 9000, Belgium
Investigational Site Number : 0560003

Brussels, 1200, Belgium
Investigational Site Number : 0560004

Gesves, 5340, Belgium
Investigational Site Number : 1240001

Québec, Quebec, G1V 4G5, Canada
Investigational Site Number : 1240002

Montreal, Quebec, H4A 3J1, Canada
Investigational Site Number : 1240003

Québec, Quebec, G1V 4W2, Canada
Investigational Site Number : 1240005

London, Ontario, N6A 4V2, Canada
Investigational Site Number : 1240009

Trois-Rivières, Quebec, G8T 7A1, Canada
Investigational Site Number : 1240012

Québec, Quebec, G2J 0C4, Canada
Investigational Site Number : 1520001

Santiago, Reg Metropolitana de Santiago, 7500505, Chile
Investigational Site Number : 1520002

Concepción, Biobio, 4070094, Chile
Investigational Site Number : 1520003

Santiago, Reg Metropolitana de Santiago, 7500692, Chile
Investigational Site Number : 1560001

Beijing, 100730, China
Investigational Site Number : 1560002

Shanghai, 200127, China
Investigational Site Number : 1560003

Zibo, 255036, China
Investigational Site Number : 1560004

Baotou, 014040, China
Investigational Site Number : 2500004

Marseille, 13005, France
Investigational Site Number : 2500005

Montpellier, 34295, France
Investigational Site Number : 2500010

Poitiers, 86021, France
Investigational Site Number : 2500012

La Rochelle, 17019, France
Investigational Site Number : 4100001

Seoul, Seoul-teukbyeolsi, 07061, South Korea
Investigational Site Number : 4100002

Seoul, Seoul-teukbyeolsi, 06351, South Korea
Investigational Site Number : 4100003

Seoul, Seoul-teukbyeolsi, 03080, South Korea
Investigational Site Number : 4100004

Seoul, Seoul-teukbyeolsi, 03722, South Korea
Investigational Site Number : 4100005

Cheonan-si, Chungcheongnam-do, 31116, South Korea
Investigational Site Number : 6160001

Warsaw, Masovian Voivodeship, 00-909, Poland
Investigational Site Number : 6160002

Poznan, Greater Poland Voivodeship, 60-693, Poland
Investigational Site Number : 6160004

Bielsko-Biala, Silesian Voivodeship, 43-300, Poland
Investigational Site Number : 6160006

Krakow, Lesser Poland Voivodeship, 31-513, Poland
Investigational Site Number : 6160008

Lodz, Lódzkie, 90-302, Poland
Investigational Site Number : 6200001

Guimarães, 4800-055, Portugal
Investigational Site Number : 6200002

Porto, 3814-501, Portugal
Investigational Site Number : 6420001

Brasov, 500283, Romania
Investigational Site Number : 6420002

Bucharest, 022328, Romania
Investigational Site Number : 7240001

Seville, Sevilla, 41009, Spain
Investigational Site Number : 7240002

L'Hospitalet de Llobregat, Catalunya [Cataluña], 08907, Spain
Investigational Site Number : 7240003

Barcelona, Barcelona [Barcelona], 08003, Spain
Investigational Site Number : 7240004

Jerez de la Frontera, Cádiz, 11407, Spain
Investigational Site Number : 7240005

Pamplona, Navarre, 31008, Spain
Investigational Site Number : 7240006

Madrid, 28040, Spain
Modena Allergy + Asthma- Site Number : 8400005

La Jolla, California, 92037, United States
Sacramento Ear Nose & Throat - Roseville- Site Number : 8400008

Roseville, California, 95661, United States
Treasure Valley Medical Research- Site Number : 8400022

Boise, Idaho, 83706, United States
United Medical Doctors - Murrieta- Site Number : 8400001

Murrieta, California, 92563, United States
Western States Clinical Research- Site Number : 8400009

Wheat Ridge, Colorado, 80033, United States

Conditions

Explore the condition pages connected to this study.

CHRONIC RHINOSINUSITIS WITHOUT NASAL POLYPS