New drug may stop transplant complications in blood cancer patients

NCT ID NCT04859946

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 26 times

Summary

This study tests whether adding the drug itacitinib to standard care can prevent graft-versus-host disease (GVHD) in people who have received a donor stem cell transplant for blood disorders. GVHD happens when donor cells attack the patient's body. The trial includes 31 adults aged 18 to 70. Itacitinib is given after transplant to try to stop this attack. This is a phase 2 study, meaning it is still being tested for safety and effectiveness.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.