Wearable device could simplify multiple myeloma treatment

NCT ID NCT06356571

Recruiting now Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new method of giving the drug isatuximab (Sarclisa) under the skin using a wearable device, combined with two other drugs (carfilzomib and dexamethasone), in 64 adults with multiple myeloma that has returned or not responded to prior therapy. The main goal is to see how many patients respond to the treatment. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

isatuximab (Sarclisa) given under the skin via a wearable device, plus carfilzomib and dexamethasone

What this could lead to

If it works, this could offer a more convenient way to deliver a combination therapy for multiple myeloma that has come back or stopped responding to treatment.

What could go wrong

This is an early-phase (Phase 2) study with only 64 participants, so results may not apply to everyone. Side effects from the drugs or the injection device are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLASMA CELL MYELOMA REFRACTORY

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Alliance for Multispeciality Research - Kansas City- Site Number : 8400056
RECRUITING

Kansas City, Missouri, 64114, United States
BRCR Global- Site Number : 8400008
RECRUITING

Plantation, Florida, 33322, United States
Beth Israel Deaconess Medical Center - Boston- Site Number : 8400005
RECRUITING

Boston, Massachusetts, 02215, United States
Center for Rheumatology, Immunology and Arthritis- Site Number : 8400031
RECRUITING

Fort Lauderdale, Florida, 33309, United States
D&H Pompano Research Center- Site Number : 8400049
RECRUITING

Margate, Florida, 33063, United States
Duke University Medical Center- Site Number : 8400018
RECRUITING

Durham, North Carolina, 27710, United States
Florida Cancer Specialists - North- Site Number : 8400030
RECRUITING

St. Petersburg, Florida, 33705, United States
Gabrail Cancer Center- Site Number : 8400010
RECRUITING

Canton, Ohio, 44718, United States
Gibbs Cancer Center & Research Institute - Spartanburg- Site Number : 8400001
RECRUITING

Spartanburg, South Carolina, 29303, United States
Hackensack Meridian Health - Hackensack University Medical Center- Site Number : 8400021
RECRUITING

Hackensack, New Jersey, 07601, United States
Hematology Oncology Consultants - Royal Oak- Site Number : 8400039
RECRUITING

Royal Oak, Michigan, 48073, United States
Life Clinical Trials - Coral Springs- Site Number : 8400055
RECRUITING

Coral Springs, Florida, 33071, United States
Los Angeles Hematology Oncology Medical Group- Site Number : 8400027
RECRUITING

Los Angeles, California, 90017, United States
Maryland Oncology Hematology- Site Number : 8400038
RECRUITING

Washington D.C., District of Columbia, 20017, United States
Mayo Clinic in Arizona - Phoenix- Site Number : 8400058
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic in Florida- Site Number : 8400002
RECRUITING

Jacksonville, Florida, 32224, United States
Memorial Sloan Kettering Cancer Center - New York - York Avenue- Site Number : 8400003
RECRUITING

New York, New York, 10065, United States
Michigan Hematology & Oncology Consultants - Dearborn- Site Number : 8400036
RECRUITING

Dearborn, Michigan, 48126, United States
Millennium Oncology - Pembroke Pines- Site Number : 8400011
RECRUITING

Pembroke Pines, Florida, 33024, United States
Northern Virginia Oncology Group- Site Number : 8400045
RECRUITING

Fairfax, Virginia, 22031, United States
Oncology Hematology Care - Kenwood- Site Number : 8400014
RECRUITING

Cincinnati, Ohio, 45236, United States
Pontchartrain Cancer Center - Covington- Site Number : 8400046
RECRUITING

Covington, Louisiana, 70433, United States
Prisma Health Cancer Institute - Greenville- Site Number : 8400019
RECRUITING

Greenville, South Carolina, 29615, United States
Private Practice - Dr. James R. Berenson- Site Number : 8400044
RECRUITING

West Hollywood, California, 90069, United States
Roper Saint Francis Healthcare- Site Number : 8400013
RECRUITING

Charleston, South Carolina, 29401, United States
SSM Health Dean Medical Group - Wisconsin - Madison- Site Number : 8400009
RECRUITING

Madison, Wisconsin, 53715, United States
San Juan Oncology Associates- Site Number : 8400016
RECRUITING

Farmington, New Mexico, 87401, United States
Smilow Cancer Center at Yale-New Haven- Site Number : 8400020
RECRUITING

New Haven, Connecticut, 06511, United States
Tennessee Cancer Specialists - Knoxville - Old Weisgarber Road- Site Number : 8400035
RECRUITING

Knoxville, Tennessee, 37909, United States
Tennessee Oncology Nashville- Site Number : 8400012
RECRUITING

Nashville, Tennessee, 37203, United States
The Oncology Institute of Hope & Innovation - Lakeland- Site Number : 8400054
RECRUITING

Lakeland, Florida, 33812, United States
University of Cincinnati Medical Center- Site Number : 8400043
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Tennessee Medical Center- Site Number : 8400006
RECRUITING

Knoxville, Tennessee, 37920, United States
Washington University- Site Number : 8400007
RECRUITING

St Louis, Missouri, 63110, United States