Iron infusions may ease POTS symptoms in small trial
NCT ID NCT07197905
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This pilot study tests whether giving intravenous iron to people with POTS who have low iron stores can increase their blood volume and reduce symptoms like rapid heart rate upon standing. The study will enroll 12 adults aged 18-45 with confirmed POTS and low ferritin levels. Participants will receive one IV iron infusion, and researchers will measure changes in heart rate during a tilt table test.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intravenous iron
What this could lead to
If it works, this could point toward a simple iron infusion treatment to reduce rapid heart rate and improve daily symptoms for people with POTS.
What could go wrong
This is a very small pilot study with only 12 participants, so results may not apply to everyone. It is also early-stage, so the treatment may not show clear benefit or could cause side effects like allergic reactions.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Autonomic Dysfunction Center/ Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States