New pill aims to halt rare kidney disease progression

NCT ID NCT05755386

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an oral medication called iptacopan can help people with a rare kidney disease called idiopathic immune-complex-mediated membranoproliferative glomerulonephritis (IC-MPGN). About 106 adults and adolescents will take either iptacopan or a placebo pill, in addition to their standard care, to see if it reduces protein in their urine, protects their kidney function, and lessens their fatigue. The goal is to control the disease and slow its progression.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Baylor Scott and White Research
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Temple, Texas, 76502, United States

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Boston Univ School of Medicine
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Boston, Massachusetts, 02118, United States

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Childrens Hospital Colorado
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Aurora, Colorado, 80045, United States

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Col Uni Med Center New York Presby
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New York, New York, 10032, United States

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Massachusetts General Hospital
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Boston, Massachusetts, 02114, United States

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Nicklaus Childrens Hospital
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Miami, Florida, 33155, United States

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Novartis Investigative Site
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CABA, Buenos Aires, C1425AGC, Argentina
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CABA, Buenos Aires, C1425EFD, Argentina
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Buenos Aires, W3400ABH, Argentina
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CABA, C1181ACH, Argentina
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Santa Fe, S3000EPV, Argentina
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Fortaleza, Ceará, 60430 370, Brazil
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Brasília, Federal District, 71635-580, Brazil
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Belo Horizonte, Minas Gerais, 30150-221, Brazil
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Recife, Pernambuco, 50740-900, Brazil
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Niterói, Rio de Janeiro, 24020 096, Brazil
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Rio de Janeiro, Rio de Janeiro, 22211-230, Brazil
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Natal, Rio Grande do Norte, 59012 300, Brazil
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Porto Alegre, Rio Grande do Sul, 90035-074, Brazil
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Botucatu, São Paulo, 18618-970, Brazil
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Santo André, São Paulo, 09090-790, Brazil
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Sao Jose Rio Preto, São Paulo, 15090-000, Brazil
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São Paulo, São Paulo, 04038-002, Brazil
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São Paulo, São Paulo, 05403 000, Brazil
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São Paulo, São Paulo, 05403-000, Brazil
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Salvador, 40323-010, Brazil
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Etobicoke, Ontario, M9W 6V1, Canada
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Toronto, Ontario, M5G 2C4, Canada
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Montreal, Quebec, H2X 1R9, Canada
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Montreal, Quebec, H3T 1C5, Canada
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Prague, 128 08, Czechia
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Aarhus N, 8200, Denmark
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Copenhagen, DK-2100, Denmark
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Marseille, 13005, France
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Montpellier, 34295, France
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Paris, 75015, France
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Rennes, 35033, France
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Toulouse, 31054, France
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Munich, Bavaria, 81377, Germany
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Würzburg, Bavaria, 97080, Germany
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Dresden, Saxony, 01307, Germany
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Jena, Thuringia, 07740, Germany
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Berlin, 13353, Germany
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Essen, 45147, Germany
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Hamburg, 20246, Germany
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Hanover, 30625, Germany
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Mainz, 55131, Germany
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Ulm, 89081, Germany
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Athens, 115 27, Greece
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Chaïdári, 124 62, Greece
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Heraklion Crete., 715 00, Greece
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Ioannina, 455 00, Greece
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Pátrai, 265 04, Greece
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Thessaloniki, 54636, Greece
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Bangalore, Karnataka, 560004, India
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Nagpur, Maharashtra, 440015, India
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Pune, Maharashtra, 411011, India
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New Delhi, National Capital Territory of Delhi, 110029, India
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Hyderabad, Telangana, 500082, India
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Haifa, 3109601, Israel
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Jerusalem, 9103102, Israel
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Petah Tikva, 4920235, Israel
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Bari, BA, 70124, Italy
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Ranica, BG, 24020, Italy
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Brescia, BS, 25123, Italy
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Milan, MI, 20122, Italy
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Roma, RM, 00165, Italy
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Torino, TO, 10126, Italy
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Naples, 80131, Italy
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Fuchū, Tokyo, 1838561, Japan
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Hachiōji, Tokyo, 193-0998, Japan
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Okayama, 7008558, Japan
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Osaka, 558-8558, Japan
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Groningen, 9713 GZ, Netherlands
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Poznan, Greater Poland Voivodeship, 60-355, Poland
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Bialystok, 15-540, Poland
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Krakow, 30-688, Poland
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Olsztyn, 10-561, Poland
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Warsaw, 02-006, Poland
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Warsaw, 02-097, Poland
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Wroclaw, 50-417, Poland
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Martin, Slovakia, 036 59, Slovakia
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Košice, 041 90, Slovakia
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Seoul, Korea, 03080, South Korea
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Seoul, 03722, South Korea
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Pamplona, Navarre, 31008, Spain
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Almería, 04009, Spain
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Barcelona, 08035, Spain
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Barcelona, 08036, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Madrid, 280796, Spain
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Salamanca, 37007, Spain
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Bern, 3010, Switzerland
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Lausanne, 1011, Switzerland
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Zurich, 8091, Switzerland
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Kaohsiung City, 81346, Taiwan
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Istanbul, Fatih, 34093, Turkey (Türkiye)
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Izmir, Karsiyaka, 35575, Turkey (Türkiye)
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Köseköy, Kocaeli, 41380, Turkey (Türkiye)
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Kayseri, Melikgazi, 38039, Turkey (Türkiye)
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Ankara, Yenimahalle, 06500, Turkey (Türkiye)
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Mersin, Yenisehir, 33110, Turkey (Türkiye)
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Belfast, BT9 7AB, United Kingdom
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Cardiff, CF14 4XW, United Kingdom
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London, NW3 2QG, United Kingdom
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London, WC1N 3JH, United Kingdom
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Manchester, M13 9WL, United Kingdom
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Salford, M6 8HD, United Kingdom
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Ho Chi Minh City, 700000, Vietnam
OHSU Dept of Nephrology
RECRUITING

Portland, Oregon, 97239, United States

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Olive View UCLA Medical Center
RECRUITING

Sylmar, California, 91342, United States

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Prolato Clinical Research Center
RECRUITING

Houston, Texas, 77054, United States

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Ronald Reagan UCLA Medical Center
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Los Angeles, California, 90095, United States

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UCSF
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San Francisco, California, 94115, United States

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Univ Cali Irvine ALS Neuromuscular
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Orange, California, 92868, United States

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Univ of Pennsylvania Medical Center
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Philadelphia, Pennsylvania, 19104, United States

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University Of Cincinnati
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Cincinnati, Ohio, 45267, United States

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University of Minnesota
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Minneapolis, Minnesota, 55455, United States

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University of New Mexico
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Albuquerque, New Mexico, 87131-0001, United States

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University of Utah
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Salt Lake City, Utah, 84113, United States

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University of Wisconsin
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Madison, Wisconsin, 53792, United States

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Washington University in St Louis
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St Louis, Missouri, 63110, United States

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Conditions

Explore the condition pages connected to this study.

IC-MPGN