New hope for kids with rare kidney disease: drug aims to cut protein leak

NCT ID NCT06994845

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 26 times

Summary

This study tests an oral drug called iptacopan in 31 children aged 2 to under 18 with IgA nephropathy, a kidney disease that can lead to kidney failure. The goal is to see if the drug reduces protein in the urine, a sign of kidney damage, and to check its safety. Participants take the drug for several months and have regular blood and urine tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Childrens Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Childrens Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104-4399, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Novartis Investigative Site

    RECRUITING

    Brisbane, Queensland, 4101, Australia

  • Novartis Investigative Site

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • Novartis Investigative Site

    RECRUITING

    Hangzhou, Zhejiang, 310052, China

  • Novartis Investigative Site

    RECRUITING

    Beijing, 100034, China

  • Novartis Investigative Site

    RECRUITING

    Hong Kong, 999077, Hong Kong

  • Novartis Investigative Site

    RECRUITING

    Beersheba, 8457108, Israel

  • Novartis Investigative Site

    RECRUITING

    Haifa, 3109601, Israel

  • Novartis Investigative Site

    RECRUITING

    Jerusalem, 9103102, Israel

  • Novartis Investigative Site

    RECRUITING

    Petah Tikva, 4920235, Israel

  • Novartis Investigative Site

    RECRUITING

    Kurume, Fukuoka, 830-0011, Japan

  • Novartis Investigative Site

    RECRUITING

    Ohtsu, Shiga, 5202192, Japan

  • Novartis Investigative Site

    RECRUITING

    Fuchū, Tokyo, 1838561, Japan

  • Prim Childrens Hosp Inv Pharm

    RECRUITING

    Salt Lake City, Utah, 84113, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.