New pill tested to slow scarring lung disease

NCT ID NCT05671835

Completed Disease control Sponsor: Tvardi Therapeutics, Incorporated Source: ClinicalTrials.gov ↗

Summary

This study tested a new oral medication called TTI-101 for people with idiopathic pulmonary fibrosis (IPF), a disease that causes permanent scarring in the lungs. For 12 weeks, 100 participants took either the drug or a placebo pill to see how safe it was and how their bodies processed it. The main goal was to check for side effects, not to prove the drug could improve lung function.

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Contacts and locations

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Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
Baylor Scott & White Center for Advanced Heart & Lung Disease

Dallas, Texas, 75246, United States
Clinical Trials Center of Middle Tennessee

Franklin, Tennessee, 37067, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Inova Fairfax Medical Campus

Falls Church, Virginia, 22042, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Metroplex Pulmonary and Sleep Center

McKinney, Texas, 75069, United States
New York University Langone Pulmonary and Critical Care Associates

Brooklyn, New York, 10017, United States
Northwestern University

Chicago, Illinois, 60611, United States
Penn State Health Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Pulmonix

Greensboro, North Carolina, 27403, United States
Saint Francis Sleep Allergy and Lung Institute

Clearwater, Florida, 33765, United States
Saint Luke's University Hospital - Bethlehem

Bethlehem, Pennsylvania, 18020, United States
Salem Chest Specialists

Winston-Salem, North Carolina, 27103-4007, United States
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
The Kirklin Clinic of University of Alabama Birmingham Hospital

Birmingham, Alabama, 35233, United States
The Lung Research Center

Chesterfield, Missouri, 63017, United States
The Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Tulane University School of Medicine

New Orleans, Louisiana, 70112-2600, United States
UHealth - University of Miami Health Systems

Miami, Florida, 33125, United States
University of California Irvine (UCI) Health

Orange, California, 92868, United States
University of California San Diego

La Jolla, California, 92037, United States
University of Chicago Medicine

Chicago, Illinois, 60637, United States
University of Colorado School of Medicine

Aurora, Colorado, 80045, United States
University of Florida

Gainesville, Florida, 32610, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States
University of Texas Health Science Center at Houston (UT Health)

Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.

IDIOPATHIC PULMONARY FIBROSIS