New way to deliver chemo may boost survival in stomach cancer patients

NCT ID NCT07304271

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether giving chemotherapy directly into the abdomen (intraperitoneal paclitaxel) along with standard systemic therapy improves survival compared to systemic therapy alone in stomach cancer patients whose cancer has spread to the lining of the abdomen. About 262 participants will be randomly assigned to one of the two groups. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Paclitaxel given directly into the abdomen (intraperitoneal)

What this could lead to

If it works, this could offer a new first-line treatment option that improves survival for gastric cancer patients with peritoneal spread.

What could go wrong

This is a phase 3 trial, but the benefit is uncertain. The added intraperitoneal treatment may cause side effects or not improve survival enough to change practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Universitaria Integrata Verona

    NOT_YET_RECRUITING

    Verona, 37126, Italy

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Karolinska University Hospital

    RECRUITING

    Stockholm, 171 76, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sahlgrenska University Hospital

    NOT_YET_RECRUITING

    Gothenburg, 413 46, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Uppsala University Hospital

    NOT_YET_RECRUITING

    Uppsala, SE-751 85, Sweden

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Örebro University Hospital

    NOT_YET_RECRUITING

    Örebro, SE-701 85, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact