Bone injection could ease dental pain for children with MIH

NCT ID NCT07457450

Ongoing Symptom relief Sponsor: University of Zagreb Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two numbing methods for children aged 6–14 with molar incisor hypomineralization (MIH), a condition that makes teeth sensitive and hard to treat. Each child will receive both an intraosseous injection (into the jawbone) and a standard gum injection on different molars. The goal is to see which method provides better pain relief during dental fillings and reduces anxiety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intraosseous anesthesia (local anesthetic injected into the bone)
What this could lead to: If it works, dentists may have a better way to numb painful MIH teeth in children, making dental visits less stressful.
What could go wrong: This is a small, early-stage study with only 50 children. The technique may not work for everyone and could cause discomfort during injection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MOLAR INCISOR HYPOMINERALISATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MOLAR INCISOR HYPOMINERALISATION

Contacts and locations

Locations

School of Dental Medicine University of Zagreb

Zagreb, 10 000, Croatia

More trials for these conditions

Other studies related to the condition(s) this trial covers.