Bone injection could ease dental pain for children with MIH

NCT ID NCT07457450

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two numbing methods for children aged 6–14 with molar incisor hypomineralization (MIH), a condition that makes teeth sensitive and hard to treat. Each child will receive both an intraosseous injection (into the jawbone) and a standard gum injection on different molars. The goal is to see which method provides better pain relief during dental fillings and reduces anxiety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intraosseous anesthesia (local anesthetic injected into the bone)

What this could lead to

If it works, dentists may have a better way to numb painful MIH teeth in children, making dental visits less stressful.

What could go wrong

This is a small, early-stage study with only 50 children. The technique may not work for everyone and could cause discomfort during injection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • School of Dental Medicine University of Zagreb

    Zagreb, 10 000, Croatia