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Could a common ointment be safe for the nose? a new study investigates

NCT ID NCT07698938

Knowledge-focused Sponsor: Hospital Universitario Dr. Jose E. Gonzalez Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 15, 2026 · Updated 2 times

Summary

This study tests whether applying Neosporin—a triple-antibiotic ointment—inside the nose is safe for healthy adults. Participants apply the ointment daily for 15 days and record any side effects. Nasal swabs are taken before and after to see how the bacteria in the nose change. The goal is to fill a gap in knowledge, since this common practice has never been formally studied.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Neosporin (polymyxin B sulfate, bacitracin zinc, neomycin sulfate)
What this could lead to
If safe, this could support using Neosporin inside the nose for preventing or treating infections in clinical practice.
What could go wrong
This is a very small early study with only 12 healthy participants, so results may not apply to everyone. Allergic reactions or antibiotic resistance are possible risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Feb 2025

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Signed informed consent * Healthy volunteers Exclusion Criteria: * Chronic or recurrent nasal conditions * Current use of other intranasal medications * History of severe allergic reactions to antibiotics * History of allergy to the components of Neosporin® * Participation in another research protocol * Being a staff member or an immediate family member of a staff member * Pregnant women

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Teste the safety of (polymyxin B sulfate 500,000 iu, bacitracin zinc 40,000 iu, neomycin sulfate 0.35G neomycin base) intranasally

Contacts and locations

Locations

  • Hospital Universitario "Dr. José Eleuterio González"

    Monterrey, Nuevo León, 64460, Mexico