Nasal spray may offer fast relief for hives sufferers

NCT ID NCT05496465

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 15 times

Summary

This study tested a single dose of a nasal spray called ARS-1 (intranasal epinephrine) to see if it can quickly reduce itching and hives during sudden flare-ups in people with frequent urticaria. 21 adults with chronic hives who still had flares despite regular treatment took part. The spray was compared to a placebo to measure how fast and how long it worked on symptoms.

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Contacts and locations

Locations

  • Bernstein Clinical Research Center, LLC

    Cincinnati, Ohio, 45236, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.