New approach: antibiotics delivered straight to the infection site during ERCP

This study tests whether giving an antibiotic (gentamicin) directly into the bile duct during a procedure called ERCP helps people with acute cholangitis recover faster. About 172 adults with mild to moderate infection will be randomly assigned to receive either the extra antibiotic or a placebo, on top of standard IV antibiotics. The main goal is to see if this approach improves infection markers and symptoms within 72 hours.