New approach: antibiotics delivered straight to the infection site during ERCP
NCT ID NCT07407491
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving an antibiotic (gentamicin) directly into the bile duct during a procedure called ERCP helps people with acute cholangitis recover faster. About 172 adults with mild to moderate infection will be randomly assigned to receive either the extra antibiotic or a placebo, on top of standard IV antibiotics. The main goal is to see if this approach improves infection markers and symptoms within 72 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gentamicin (antibiotic) given directly into the bile duct during ERCP
What this could lead to
If it works, this could lead to faster recovery and shorter hospital stays for people with acute cholangitis.
What could go wrong
This is a small, early-phase trial, so results may not be conclusive. The added antibiotic could cause side effects or not improve outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Canselor Tuanku Muhriz UKM
RECRUITINGCheras, Kuala Lumpur, 56000, Malaysia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••